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![[Webinar] Rare event analysis in flow cytometry(09/17、09/24)](/upload/activity/activity_20210907124638_0.jpg)
活動介紹
有些細胞在人體血液和組織裡含量很少但卻很重要，例如Innate Lymphoid Cells (ILC)在先天免疫系統就扮演重要角色；另在抗體治療領域上，準確解測和分析這些稀有細胞是了解疾病進程的重要關鍵。
但因為稀有，檢測上並不容易，而流式細胞儀的一大優勢是同時檢測多種細胞參數，搭配DURAClone IM ILC和DURAClone RE高靈敏度檢測試劑，能準確分析稀有細胞外，在最大程度檢測樣品下有效避免樣品損失。
是不是聽起來很不可思議，報名線上研討會來瞭解詳情。
✨ Session 1 (Sep. 17): Innate Lymphoid Cells
✨ Session 2 (Sep. 24): Abnormal rare cells of the B cell lineage
【關於美商貝克曼庫爾特】
但因為稀有，檢測上並不容易，而流式細胞儀的一大優勢是同時檢測多種細胞參數，搭配DURAClone IM ILC和DURAClone RE高靈敏度檢測試劑，能準確分析稀有細胞外，在最大程度檢測樣品下有效避免樣品損失。
是不是聽起來很不可思議，報名線上研討會來瞭解詳情。
✨ Session 1 (Sep. 17): Innate Lymphoid Cells
✨ Session 2 (Sep. 24): Abnormal rare cells of the B cell lineage
【關於美商貝克曼庫爾特】
美商貝克曼庫爾特有限公司研發、製造和行銷可將實驗室生物醫學檢驗簡化及自動化的儀器和軟體。我們產品的支援範圍從前端醫學研究到患者血液檢驗等與疾病戰鬥之各階段的生物醫學分析。2010年公司的營業額為37億美元，其中87.6%的營業額來自於臨床診斷市場，其它12.4%則來自於生物醫學研究市場。
貝克曼庫爾特的儀器業務包含了範圍廣泛的各式分離、檢驗和生命科學分析系統。對於醫院的臨床實驗室，我們的產品提供了具臨床意義的各種一般血液檢驗及75%的其它項目檢驗。我們70%以上的產品都居於市場領先位置，如血液分析儀、一般生化系統、離心機、毛細管電泳儀、蛋白質分析儀、自動化機械手臂以及快速檢驗系統。
我們的客戶涵蓋了遍及全球的製藥和生物科技公司、大學、醫學院、研究機構、醫院、醫師辦公室及臨床診斷實驗室。貝克曼庫爾特目前提供了世界各地實驗室約275,000台的儀器系統、作業系統售後服務、生化試劑及維修合約等，其約當於總業務收入的64％。
→更多貝克曼資訊貝克曼庫爾特的儀器業務包含了範圍廣泛的各式分離、檢驗和生命科學分析系統。對於醫院的臨床實驗室，我們的產品提供了具臨床意義的各種一般血液檢驗及75%的其它項目檢驗。我們70%以上的產品都居於市場領先位置，如血液分析儀、一般生化系統、離心機、毛細管電泳儀、蛋白質分析儀、自動化機械手臂以及快速檢驗系統。
我們的客戶涵蓋了遍及全球的製藥和生物科技公司、大學、醫學院、研究機構、醫院、醫師辦公室及臨床診斷實驗室。貝克曼庫爾特目前提供了世界各地實驗室約275,000台的儀器系統、作業系統售後服務、生化試劑及維修合約等，其約當於總業務收入的64％。
活動議程
| ▶Session 1 Rare event analysis in flow cytometry (I): Innate Lymphoid Cells Speaker: Michael Kapinsky(Product Manager @Beckman Coulter) Time:2021/09/17 15:00 Innate lymphoid cells (ILC) play an important role in innate immunity, lymphoid organogenesis, tissue remodeling and inflammation. While ILCs do not express an antigen-specific receptor such as found on B or T cells, they form a phenotypically and functionally heterogeneous population that can be categorized into 3 groups, i.e., ILC1, ILC2 and ILC3. ILCs can be found in various tissues including peripheral blood.
Flow Cytometric analysis of ILCs face the challenges of extremely low frequencies as well as the absence of specific markers, forcing discrimination of all leukocyte lineages with a comprehensive set of markers.To address these challenges, the new DURAClone IM ILC antibody panel accommodates analysis of enriched suspensions with high leukocyte concentrations and eliminates the pipetting of 17 antibodies, introducing a new level of standardization in flow cytometry of ILCs. |
| ▶Session 2 Rare event analysis in flow cytometry (II): Abnormal rare cells of the B cell lineage Time:2021/09/24 15:00 Rare event cytometry has emerged as a powerful and important tool in clinical research of blood disorders. Sensitive and specific detection of just a few dozens of abnormal target cells among millions of normal cells is one of the most challenging applications in flow cytometry. Antigen expression patterns of greatly abundant normal populations may overlap with the expression patterns of rare abnormal cell populations. In the era of biologics, we also need to take into account that therapeutic antibodies might mask important antigens such as CD38, preventing their detection with conventional analytical antibodies. The DURAClone RE kits consist of a carefully selected combination of antibodies and have been optimized to accomodate either large sample volume or high cellular concentrations to achieve high sensitivity for rare populations. Furthermore, a new class of camelid-derived antibodies can be used together with the DURAClone antibody panels, allowing to overcome the masking of target antigens with targeted biologics by the detection of so-called cryptic epitopes. |
