阿茲海默症症狀出現之前，腦部便有澱粉樣蛋白沉澱，這些蛋白斑塊主要成份為β-澱粉樣蛋白和APOE蛋白。近日，華盛頓大學醫學院的研究人員證實，一種抗體不僅可以將APOE靶向去除，而且可以清除斑塊。

Antibodies against APOE (red) bind to amyloid plaques (blue) in brain tissue from people with Alzheimer's disease. Researchers have found that the antibody can sweep away the damaging plaques, at least in mice, which could lead to a therapy for the devastating disease. Credit: Monica Xiong

這項26日發表在《Journal of Clinical Investigation》上的研究，也許能夠在疾病早期（可能在症狀出現之前）就阻止澱粉樣蛋白斑塊對大腦細胞造成的傷害。

神經內科主任、通訊作者David Holtzman表示，...