新世代胞外囊泡治療論壇2025

Extracellular vesicles (EVs), encompassing exosomes and microvesicles, have emerged as critical mediators of intercellular signaling and represent a transformative platform for diagnostics and therapeutics. Increasing evidence underscores their involvement in cancer progression, regenerative medicine, immune modulation, aging, and neurological disorders—positioning EVs at the forefront of next-generation biomedical innovation.

To advance translational research and global collaboration in this rapidly evolving field, China Medical University (CMU) will host the NextGen EV Therapeutics Forum on June 24, 2025, at its Shuinan Campus in Taichung, Taiwan. This high-level, full-day event will convene internationally renowned experts, including Nobel Laureate Prof. Randy W. Schekman and Prof. Kenneth W. Witwer, President of the International Society for Extracellular Vesicles (ISEV), alongside leading voices from Taiwan’s academic, clinical, and biotech sectors.

The forum will spotlight the latest breakthroughs in EV engineering, scalable manufacturing, and clinical translation, while fostering interdisciplinary dialogue and strategic alliances. Through knowledge exchange and collaborative engagement, the event aims to accelerate the integration of EV-based technologies into precision medicine and global health solutions.

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細胞外囊泡（EVs），包含外泌體與微囊泡，是細胞之間傳遞訊息的重要媒介。近年在癌症、再生醫學、免疫調控、老化與神經疾病等領域展現出高度的應用潛力，成為次世代生醫技術的重要突破口。

為推動EV技術的臨床應用與國際交流，中國醫藥大學將於2025年6月24日（星期二）在水湳校區舉辦「新世代胞外囊泡治療論壇（NextGen EV Therapeutics Forum）」。本次論壇邀請多位國內外重量級專家，包括諾貝爾獎得主 Prof. Randy W. Schekman 和國際外泌體學會（ISEV）理事長 Prof. Kenneth W. Witwer，深入探討EV在工程設計、製程放大到臨床應用的最新進展。

論壇將是連結產學、促進創新合作的重要平台，帶領大家一同邁向精準醫療與全球健康的新時代。

本活動免費參加，不論您是對生醫科技有興趣的民眾、投入研究的學者，或是關注未來醫療趨勢的產業夥伴，誠摯邀請您一同參與，掌握這波醫療科技新浪潮！

時間	主題	演講題目	演講者	主持人
08:00-08:30	報到
08:30-08:35	開場		洪明奇
08:35-09:25	主講人	Unconventional secretion of extracellular vesicles and soluble proteins	Randy Wayne Schekman	洪明奇
09:25-09:35	致詞		國科會 吳誠文主委
09:35-09:40	團體照合影
09:40-10:10	國際趨勢	Prerequisites to therapies: extracellular vesicle biodistribution, pharmacokinetics, and immunogenicity	Kenneth W. Witwer	周德陽
10:10-10:30	Tea Break
10:30-11:00	前瞻洞察	SOB100: HLA-G targeted exosome Precision Medicine Redefined	何慧君	龔行健
11:00-11:30		Unlocking the potential of tissue-specific exosome generated from induced pluripotent stem cell-derived organoids	沈家寧
11:30-12:00		Effects of extracellular vesicles on immune checkpoint and vector development for EVs to target tumor cells	洪明奇
12:00-13:20	午餐
13:20-13:50	尖端進展	Emerging roles of exosomes in precision medicine	沈湯龍	鄭隆賓
13:50-14:20		Harnessing Induced Exosome Signaling for Regenerative Medicine, Cancer Therapy, and Diagnosis	李華容
14:20-14:40	Tea Break
14:40-15:00	創新技術發展	Engineered extracellular vesicles for in vivo generation of CAR-T cells against soldi tumors and prospects	黃士維	周涵怡
15:00-15:20		Engineered Extracellular Vesicle-Mediated Precise Drug Delivery of Targeted Neurons for Parkinson’s Disease Therapy	謝明佑
15:20-15:40		CRISPR-Engineered Stem Cells for Targeted Delivery of Mitochondrial Extracellular Vesicles in MASLD Treatment	王志豪
15:40-16:00		Cardiac Repair Effect of Engineer Exosomes in Heart Failure with Reduced Ejection Fraction	林晏年
16:00-16:30	Panel Discussion		周德陽
16:30	閉幕式