雙抗開發:上游挑戰與策略

雙抗開發:上游挑戰與策略

We will discuss initial strategies to optimize the amino acid sequence of the molecule and techniques to maximize product safety and quality. GS piggyBac®, which can help improve expression levels for more complex next-generation biologics, will also be discussed.

活動介紹

[Webinar]Bispecific Antibody Development: Upstream Challenges and Strategies

GEN: On-Demand Webinar

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【Summary】

Biological pipelines are evolving from standard antibody formats to next-generation biologics such as bispecific antibodies (bsAbs). However, these molecules are often difficult to express and it is a challenge to develop productive processes. There is a real need for an expression platform that can keep pace with these requirements. 
 

In this webinar replay, Dr. Jizu Yi shares his experiences with key upstream challenges for the expression of YBODY® and CHECKBODY® based bsAbs. Dr. Yi discusses how his lab successfully developed strategies using the GS Xceed® Expression System to construct cell lines with high productivity and product quality in a short time span—concluding with how his organization managed to control the level of impurities during manufacturing. 


The GS Xceed® Expression System is a market-leading expression technology platform. This robust, fully integrated, scalable system includes host cell lines, vectors, and access to optimized media and feeds, as well as comprehensive methods and processes.


To learn more about GS piggyBac®, you can also visit our website.