歡迎來到 BIO Asia-Taiwan,親自認識 Invion(澳洲上市公司,股票代碼 ASX: IVX)執行主席兼執行長 Thian Chew 教授!
Invion 是一家臨床階段的生技公司,致力於開發下一代光動力治療(Photodynamic Therapy, PDT)技術——Photosoft,用於治療多種癌症與傳染性疾病。
Invion 近期公佈了第二期攝護腺癌臨床試驗的正面結果,反應率達 40%,且安全性表現良好。目前也正進行皮膚癌的一期/二期臨床試驗,並預計在未來 12 至 24 個月內展開更多針對其他癌症的試驗。
此外,Invion 已與韓國 Hanlim Pharma 與 Dr. inB 簽署合作協議,對方將出資並進行研究,探索使用 Photosoft 治療腦部惡性腫瘤(膠質母細胞瘤 GBM)、食道癌及人類乳突病毒(HPV)相關疾病的潛力。
Invion 的研究合作夥伴——彼得·麥卡倫癌症中心(Peter MacCallum Cancer Centre)與哈德遜醫學研究所(Hudson Institute of Medical Research)所進行的前臨床研究顯示,該技術可完全抑制多種癌症(例如三陰性乳癌與卵巢癌),並能激發人體免疫系統持續對抗癌細胞。
Invion 已開發出一系列受專利保護的化合物,其主要藥物候選為 INV043,一種新型光敏劑,具有同時作為治療與診斷工具的潛力。
Come and meet Prof. Thian Chew, the Executive Chair and CEO of Australian-listed Invion (ASX: IVX) at BIO Asia-Taiwan! Invion is a clinical-stage company developing the next-generation Photodynamic Therapy (PDT), called Photosoft, for the treatment of a range of cancers and infectious diseases.
Invion released positive results from a Phase II prostate cancer trial with a 40% response rate and a strong safety profile. It is undertaking a Phase I/II trial on skin cancer with more trials to treat other cancers scheduled over the next 12-24 months.
Additionally, Invion signed agreements with Hanlim Pharma and Dr. inB.
They will fund and undertake studies using Photosoft to treat brain malignancy GBM, oesophageal cancer and Human Papilloma Virus (HPV).
Pre-clinical results undertaken by Invion's research partners, the Peter MacCallum Cancer Centre and Hudson Institute of Medical Research, showed that the technology completely regressed a range of cancers, such as triple negative breast and ovarian cancers, and stimulated the body's immune system to continue fighting the cancer.
Invion has developed a portfolio of patent protected compounds. Its lead drug candidate is INV043, a novel photosensitiser which has the potential to work as a therapy and a diagnostic tool.